Reward system -  Dopamine Binding at the Neuron Level

The primary neurotransmitter of the reward pathway is dopamine (1,2,3,4). Although drugs of abuse often act through separate mechanisms and on various locations in the brain reward system, they share a final common action in that they increase dopamine levels in the brain reward system.  However, neurotransmitter systems are inextricably intertwined.  Thus serotonin, endogenous opiates, as well as GABA also modulate dopamine levels in the brain reward pathway (1,2,3).  In the following paragraphs the major neurotransmitters involved in brain reward will be discussed.

Reference: http://ibgwww.colorado.edu/cadd/a_drug/essays/essay4.htm 

Read More:Reward system - Neuroanatomy and Physiology of the “Brain Reward System” | Reward system - The Structures of the Reward Pathway | Reward system - Electrical Stimulation of the Brain Reward Pathway | Reward system - Molecular Physiology of the Reward Pathway | Serotonin - Neurotransmitters and Brain Reward | Reward system - GABA | Reward system - Endorphin Binding at the Synapse

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